Next Steps: Gene Therapy for Dravet Syndrome – Moran Rubinstein & Eric Kremer 2/2

Hear about how an exciting Dravet gene therapy is to be used (treating the cause rather than the symptoms), the extraordinary benefits, but also the next steps and the long journey from patent - pharma - patient! All from scientists Moran Rubinstein from Tel Aviv University in Israel and Eric Krema from Universite de Montpellier in France.
If you haven’t seen the first episode from Moran and Eric, check it out here.

• About Moran & Eric

  Moran Rubinstein is an Asst. Prof. and the PI of the Rubinstein Lab at Tel Aviv University in Israel. Moran’s projects focus on three forms of developmental epileptic encephalopathy: Dravet Syndrome, GRIN2D, and CHD2, where the neuronal and molecular basis of visual system abnormalities in severe epilepsy and autism are studied.

  Eric Kremer is the Director of Research at the French National Institute of Health and Medical Research (INSERM) and Director of a research lab at the Institut de Génétique Moléculaire de Montpellier (IGMM) in France. His lab develops and studies viral tools for gene therapy of neurological and other diseases.

  Special thanks
  Moran and Eric give thanks to their project team members:

  Saja Fadial, Bertrand Beucher, Iria González-Dopeso Reyes, Anat Mavashov, Marina Brusel, and Karen Anderson.

  They would also like to thank other members of their team: Yael Almog, Shir Quinn, Mor Yam, Shaked Turk, and Jolan Nasir.

• Links to Moran & Eric

  Moran:

  Relevant paper | Dravet Syndrome Foundation | Twitter | LinkedIn | Lab | Tel Aviv University - profile | ResearchGate | Orcid | Loop | PubMed | Google Scholar | Cell | AES | RAMOT | CRIS | Scorpus

  Eric:

  Relevant paper | Dravet Syndrome Foundation | Lab | IGMM – Institut de Génétique Moléculaire de Montpellier | ResearchGate | PubMed | Orcid | Cell | AES | Loop | Google Scholar

• Glossary

  Terms used and added to Glossary:

  Cell membrane

  Channelopathy

  Coding sequence

  Interictal spikes

  Ions

  Neurodegenerative disease

  Terms used but already in Glossary:

  Autism

  Epileptic encephalopathies

  Interictal

  Phenotype

  Vectors

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